Frataxin antibody (AA 42-210)

Catalog No. ABIN5776114

The Mouse Monoclonal anti-Frataxin antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect Frataxin in samples from Human.

Quick Overview for Frataxin antibody (AA 42-210) (ABIN5776114)

Target: Frataxin (FXN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT10E11

Product Details anti-Frataxin Antibody

Binding Specificity: AA 42-210

Purpose: Human Frataxin antibody

Purification: Purified

Immunogen: Recombinant human Frataxin (42-210aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: Frataxin

Background: Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia.

NCBI Accession: NP_000135

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size